Article
Mechanisms of disease: infection and spondyloarthritis.
Nature clinical practice. Rheumatology - 1 Mar 2006
Inman Robert D
Abstract excerpt
There is compelling evidence that some infections can initiate a chronic nonseptic arthritis. This has proved to be an important area of investigation into gene-environment interactions, particularly since HLA-B27 confers increased susceptibility to reactive arthritis. This research has investigated the microbiology of these events, and the strategies used by pathogens to induce chronic joint inflammation....
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