Article
HLA and disease.
Molecular aspects of medicine - 1 Jan 1992
Baines M, Ebringer A
Abstract excerpt
Many human diseases are associated with HLA class I, class II and class III antigens. It appears that the class III antigen disease associations can be explained by a direct defect operating at the level of either the class III gene or its gene product. The mechanism underlying class I and class II antigen disease associations is at present unknown. In this review we have considered thirty diseases which have...
Topics
- Antigen-Presenting Cells
- Antigens
- Autoimmune Diseases
- Cross Reactions
- Disease Susceptibility
- Ethnicity
- Gene Frequency
- Genetic Predisposition to Disease
- HLA Antigens
- Histocompatibility Testing
- Humans
- Major Histocompatibility Complex