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Article

Homozygous arginine at codon 72 of p53 has no prognostic significance in cervical cancer.

Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine - 1 Jan 2000

Ngan H Y, Liu V W, Liu S S, Cheng D K, Ng T Y, Wong L C

Abstract excerpt

Mutation of p53, a tumour suppressor gene, is uncommon in cervical cancer but the detection of human papillomavirus (HPV) DNA in cervical cancer is common. The findings of increased susceptibility to degradation of p53 by E6 protein of HPV16/18 in cervical cancer with homozygous arginine at codon 72 (HA72) of p53 led to this study on whether cervical cancers with HA72 were more aggressive with the increase in the...

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PMID: 10754463
DOI: 10.1159/000030119

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Homozygous arginine at codon 72 of p53 has no prognostic significance in cervical cancer.PMID 10754463Read ↗

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