Article
Predominance of one T-cell antigen receptor BV haplotype in African populations.
Immunogenetics - 1 Mar 2000
Craddock T P, Zumla A M, Ollier W E, Chintu C Z, Muyinda G P, Lancaster F C, Boylston A W
Abstract excerpt
The human T-cell antigen receptor (TCR) is the counter-receptor for the HLA/peptide complex displayed on the surface of antigen-presenting cells. It confers antigen specificity on T lymphocytes and therefore plays a central role in pathogen recognition and host response. The most frequently used form of the TCR is a heterodimer composed of variable alpha and beta chains. We investigated allele frequencies for...
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