Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Malaria is not responsible for the selection of TCR beta-subunit variable gene haplotypes in The Gambia.

Immunogenetics - 1 Feb 2002

Donaldson Ian J, Shefta Jahan, Hill Adrian V S, Boylston Arthur W

Abstract excerpt

Previous work has shown that a single haplotype of the T-cell antigen receptor beta-subunit (TCRB) locus is predominant in African populations. This is likely to be due to selection pressure for gene(s) that protect children against disease. This study has tested the hypothesis that malaria is the responsible selection pressure, due to its impact on child mortality. The haplotypes of BV8S3, BV2S1, BV15S1, and...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Complementarity Determining Regions
Share to Gambia
Share to Genes, T-Cell Receptor beta

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Haplotypes

Share to Malaria

Share to Polymorphism, Restriction Fragment Length

Share to Receptors, Antigen, T-Cell, alpha-beta

Share to Selection, Genetic

Source

Identifiers

PMID: 11862389
DOI: 10.1007/s00251-001-0407-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 9 closest

Malaria is not responsible for the selection of TCR beta-subunit variable gene haplotypes in The Gambia.PMID 11862389Read ↗

Unique TCR beta-subunit variable gene haplotypes in Africans.Semantic proximity Read ↗

Predominance of one T-cell antigen receptor BV haplotype in African populations.Semantic proximity Read ↗

Analysis of the T-cell receptor V beta usage in monozygotic and dizygotic twins living in a Plasmodium falciparum endemic area in west Africa.Semantic proximity Read ↗

Limited MHC class II gene polymorphism in the West African chimpanzee is distributed maximally by haplotype diversity.Semantic proximity Read ↗

The lower susceptibility to Plasmodium falciparum malaria of Fulani of Burkina Faso (west Africa) is associated with low frequencies of classic malaria-resistance genes.Semantic proximity Read ↗

Selection assisted by a BoLA-DR/DQ haplotype against susceptibility to bovine dermatophilosis.Semantic proximity Read ↗

Haptoglobin genotypes are not associated with resistance to severe malaria in The Gambia.Semantic proximity Read ↗

Polymorphisms in interleukin-1beta and interleukin-1 receptor antagonist genes and malaria in Ghanaian children.Semantic proximity Read ↗

HLA class II factors associated with Plasmodium falciparum merozoite surface antigen allele families.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.