Article
The SH2D2A gene encoding the T-cell-specific adapter protein (TSAd) is localized centromeric to the CD1 gene cluster on human Chromosome 1.
Immunogenetics - 1 Mar 2000
Dai K Z, Vergnaud G, Ando A, Inoko H, Spurkland A
Abstract excerpt
The SH2D2A gene encoding the T-cell-specific adapter protein (TSAd), was isolated from a human Chromosome (Chr) 1 cosmid library (LLNL, UK HGMP). The gene spans 11 kilobases and contains nine exons and eight introns. Four alternative transcript variants were observed in activated T cells. Three single-nucleotide polymorphisms were identified within intron 2. A variable number of GA repeats was found at position...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.