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Article

Bcl-2 Immunoreactive Cells With Immature Neuronal Phenotype Exist in the Nonepileptic Adult Human Brain

1 Feb 2000

Abstract excerpt

Bcl-2, a cell death suppressor protein, is expressed during brain development but is largely down-regulated in the adult central nervous system. We previously reported strong expression of bcl-2 in small, "oligodendrocyte-like" cells (OLC) found in glioneuronal hamartias. These hamartias are microscopic cell rests found in temporal lobe resections from patients with intractable epilepsy and are considered a form...

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PMID: 10749100
DOI: 10.1093/jnen/59.2.113

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