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Article

Effect of the factor V Leiden mutation on the clinical expression of severe hemophilia A.

Thrombosis and haemostasis - 1 Mar 2000

Lee D H, Walker I R, Teitel J, Poon M C, Ritchie B, Akabutu J, Sinclair G D, Pai M, Wu J W, Reddy S, Carter C, Growe G, Lillicrap D, Lam M, Blajchman M A

Abstract excerpt

To determine whether the factor V Leiden mutation is associated with decreased bleeding in individuals with severe hemophilia A, factor concentrate utilization, maximum annual number of bleeding episodes, and the prevalence of hemophilic arthropathy between carriers and non-carriers of the factor V Leiden mutation were compared. Heterozygosity for the factor V Leiden mutation was found in 6 of 137 subjects...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 10744141

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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