Article
c-erbB-4 protein expression in human breast cancer.
British journal of cancer - 1 Mar 2000
Kew T Y, Bell J A, Pinder S E, Denley H, Srinivasan R, Gullick W J, Nicholson R I, Blamey R W, Ellis I O
Abstract excerpt
The Type 1 family of growth factor receptors includes epidermal growth factor receptor (EGFR), c-erbB-2, c-erbB-3 and c-erbB-4. Overexpression of the first two members is associated with poorer prognosis in patients with breast carcinoma. In this study we examined the expression of c-erbB-4 protein using the monoclonal antibody HFR-1. A total of 127 consecutive cases of primary operable invasive breast carcinoma...
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