c-erbB3 and c-erbB4 expression is a feature of the endocrine responsive phenotype in clinical breast cancer.

doi:10.1038/sj.onc.1202107

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Article

c-erbB3 and c-erbB4 expression is a feature of the endocrine responsive phenotype in clinical breast cancer.

Oncogene - 15 Oct 1998

Knowlden J M, Gee J M, Seery L T, Farrow L, Gullick W J, Ellis I O, Blamey R W, Robertson J F, Nicholson R I

Abstract excerpt

We examined c-erbB3 and c-erbB4 mRNA expression in 47 primary breast cancer samples by simultaneous RT-PCR and have investigated correlations between these parameters and the expression of both ER and EGFR mRNA and protein as measured by RT-PCR and ICA and with Ki67 immunostaining. A direct assoc...

Topics

Antineoplastic Agents, Hormonal
Base Sequence
Breast Neoplasms
DNA Primers
ErbB Receptors
Female
Humans
Phenotype
Postmenopause
Proto-Oncogene Proteins
RNA, Messenger
Receptor, ErbB-3
Receptor, ErbB-4
Reverse Transcriptase Polymerase Chain Reaction
Tamoxifen

Source

Open in PubMed

Identifiers

PMID: 9788438
DOI: 10.1038/sj.onc.1202107

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9788438-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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