Article
Combined heterozygous plasminogen deficiency and factor V Leiden defect in the same kindred.
Clinical and applied thrombosis/hemostasis : official journal of the International Academy of Clinical and Applied Thrombosis/Hemostasis - 1 Jan 2000
Sartori M T, Simioni P, Patrassi G M, Theodoridis P, Tormene D, Girolami A
Abstract excerpt
Combined plasminogen deficiency and resistance to activated protein C defect (factor V Leiden) have been described in a few families and associated with a variable occurrence of thrombotic events. Here we describe a new family with thrombophilia and the presence of hypoplasminogenemia and factor V Leiden mutation. In addition, a brief review of the literature is presented. Nine patients belonging to this kindred...
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