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Article

An aldose reductase intragenic polymorphism associated with diabetic retinopathy.

Diabetes research and clinical practice - 1 Nov 1999

Kao Y L, Donaghue K, Chan A, Knight J, Silink M

Abstract excerpt

The polyol pathway has been considered important in the development of diabetes long-term complications. Diabetic patients with microvascular disease have increased gene expression and enzyme activity, which may be due to variants in the aldose reductase gene. An association of an intragenic BamHI polymorphic site with diabetic retinopathy and nephropathy has been suggested, but the BamHI site has not been...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 10724095
DOI: 10.1016/s0168-8227(99)00087-x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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