Article
Evolution of α2-Fucosyltransferase Genes in Primates: Relation Between an Intronic Alu-Y Element and Red Cell Expression of ABH Antigens
1 Mar 2000
Abstract excerpt
Coding sequences of the paralogous FUT1 (H), FUT2 (Se), and Sec1 alpha 2-fucosyltransferase genes were obtained from different primate species. Analysis of the primate FUT1-like and FUT2-like sequences revealed the absence of the known human inactivating mutations giving rise to the h null alleles of FUT1 and the se null alleles of FUT2. Therefore, most primate FUT1-like and FUT2-like genes potentially code for...
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