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Article

Preimplantation embryo development (Ped) gene copy number varies from 0 to 85 in a population of wild mice identified as Mus musculus domesticus.

Mammalian genome : official journal of the International Mammalian Genome Society - 1 Nov 2007

Byrne Michael J, Jones Gwilym S, Warner Carol M

Abstract excerpt

The preimplantation embryo development (Ped) gene regulates the rate of preimplantation embryonic cleavage division and subsequent embryo survival. In the mouse, the Ped gene product is Qa-2 protein, a nonclassical MHC class I molecule encoded by four tandem genes, Q6/Q7/Q8/Q9. Most inbred strains of mice have all four genes on each allelic chromosome, making a total of eight Qa-2 encoding genes, but there are a...

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Source

Identifiers

PMID: 17990033
DOI: 10.1007/s00335-007-9067-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

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Preimplantation embryo development (Ped) gene copy number varies from 0 to 85 in a population of wild mice identified as Mus musculus domesticus.PMID 17990033Read ↗

The expression pattern of the Qa-2 antigen in mouse preimplantation embryos and its correlation with the Ped gene phenotype.Semantic proximity Read ↗

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Good copy, bad copy: choosing animal models for HLA-linked diseases.Semantic proximity Read ↗

Regulation of Ped gene expression by TAP protein.Semantic proximity Read ↗

Sexual preference of apparent gene conversion events in MHC genes of mice.Semantic proximity Read ↗

Analysis of litter size and weight in mice differing in Ped gene phenotype and the Q region of the H-2 complex.Semantic proximity Read ↗

Identification of two major histocompatibility complex class Ib genes, Q7 and Q9, as the Ped gene in the mouse.Semantic proximity Read ↗

Differential expression of Ped gene candidates in preimplantation mouse embryos.Semantic proximity Read ↗

A survey of H2 gene sequences, including new wild-derived genes.Semantic proximity Read ↗

Interspecific backcross mice show sex-specific differences in allelic inheritance.Semantic proximity Read ↗

Analysis of transcription factor AP-2 expression and function during mouse preimplantation development.Semantic proximity Read ↗

Identification of the Ped gene at the molecular level: the Q9 MHC class I transgene converts the Ped slow to the Ped fast phenotype.Semantic proximity Read ↗

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