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Article

Luteinizing hormone receptor mutations in disorders of sexual development and cancer.

Frontiers in bioscience : a journal and virtual library - 1 Mar 2000

Wu S M, Leschek E W, Rennert O M, Chan W Y

Abstract excerpt

Human male sexual development is regulated by chorionic gonadotropin (CG) and luteinizing hormone (LH). Aberrant sexual development caused by both activating and inactivating mutations of the human luteinizing hormone receptor (LHR) have been described. All known activating mutations of the LHR are missense mutations caused by single base substitution. The most common activating mutation is the replacement of...

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Identifiers

PMID: 10704433
DOI: 10.2741/wu

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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