Article
Molecular pathogenesis and diagnostics of bladder cancer.
Annual review of pathology - 1 Jan 2009
Mitra Anirban P, Cote Richard J
Abstract excerpt
Despite elaborate characterization of the risk factors, bladder cancer is still a major epidemiological problem whose incidence continues to rise each year. Urothelial carcinoma is now recognized as a disease of alterations in several cellular processes. The more prevalent, less aggressive, recurrent, noninvasive tumors are characterized by constitutive activation of the Ras-MAPK pathway. The less common but more...
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