Article
Pulmonary surfactant metabolism in infants lacking surfactant protein B.
American journal of respiratory cell and molecular biology - 1 Mar 2000
Beers M F, Hamvas A, Moxley M A, Gonzales L W, Guttentag S H, Solarin K O, Longmore W J, Nogee L M, Ballard P L
Abstract excerpt
Infants with inherited deficiency of pulmonary surfactant protein (SP) B develop respiratory failure at birth and die without lung transplantation. We examined aspects of surfactant metabolism in lung tissue and lavage fluid acquired at transplantation or postmortem from ten infants born at term with inherited deficiency of SP-B; comparison groups were infants with other forms of chronic lung disease (CLD) and...
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