Article
Transient surfactant protein B deficiency in a term infant with severe respiratory failure.
The Journal of pediatrics - 1 Feb 1998
Klein J M, Thompson M W, Snyder J M, George T N, Whitsett J A, Bell E F, McCray P B, Nogee L M
Abstract excerpt
A 38-day-old male infant with persistent pulmonary hypertension and respiratory failure since birth was found to have a complete absence of surfactant protein B (SP-B) along with an aberrant form of SP-C in his tracheal aspirate fluid, findings consistent with the diagnosis of hereditary SP-B deficiency. Surprisingly, SP-B and SP-B messenger ribonucleic acid were present in lung biopsy tissue. However, DNA...
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