Article
Interleukin 1 receptor antagonist gene polymorphism in women with vulvar vestibulitis.
American journal of obstetrics and gynecology - 1 Feb 2000
Jeremias J, Ledger W J, Witkin S S
Abstract excerpt
OBJECTIVE: Vulvar vestibulitis is a chronic inflammatory syndrome of unknown cause and pathogenesis. We examined the relation between vulvar vestibulitis and polymorphisms in the gene coding for the interleukin 1 receptor antagonist, a naturally occurring down-regulator of proinflammatory immune responses. STUDY DESIGN: Cells from the lower genital tract of 68 women with vulvar vestibulitis, 343 women with no...
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