Article
HLA-DRB genotypes in Japanese patients with renal cell carcinoma.
Oncology - 1 Jun 2000
Kojima Y, Takahara S, Nonomura N, Sada M, Tsuji T, Hatori M, Fujioka H, Kuroda H, Miki T, Okuyama A
Abstract excerpt
OBJECTIVES: Several clinical features, such as the spontaneous regression of some renal cell carcinoma (RCC) metastases after nephrectomy, suggest immune involvement in tumor destruction. PATIENTS AND METHODS: We investigated the role of genetic variation at the HLA class II loci in RCC by analyzing the HLA-DR antigen and HLA-DRB1, DRB3, DRB4 and DRB5 alleles in 55 patients using the polymerase chain rection....
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