Article
An element with palindromic structure is required for the expression of TBP (TATA box-binding protein) gene in Drosophila melanogaster.
Molecules and cells - 31 Dec 1999
Oh Y, Lee C, Baek K, Kim W, Yoon J, Han K, Cho N
Abstract excerpt
Previously we showed that the 5'-flanking regions between -261 and -207 of the Drosophila melanogaster TBP (TATA box binding protein) gene is important for its expression. We further made serial deletion mutants in this region and analyzed their promoter activities using the transient transfection assay. We found that the 16 bp deletion from -261 to -245 greatly reduces the promoter activity of the Drosophila TBP...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
