Article
Mutations of the cationic trypsinogen gene in patients with hereditary pancreatitis.
The British journal of surgery - 1 Feb 2000
Creighton J E, Lyall R, Wilson D I, Curtis A, Charnley R M
Abstract excerpt
BACKGROUND: Hereditary pancreatitis has been shown to be caused by one of two mutations (R117H and N21I) of the cationic trypsinogen gene (PRSS1). Families with hereditary pancreatitis in the north of England were investigated for these mutations. The clinical features associated with each mutation were compared. METHODS: In individuals from nine families with hereditary pancreatitis, DNA was screened for the...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.