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Article

The yin-yang of PR-domain family genes in tumorigenesis.

1 Jan 2000

Abstract excerpt

Cancer is essentially caused by alterations in normal cellular genes. Multiple gene changes involving at least two types of cancer genes, protooncogenes and tumor suppressor genes, are required for the clonal expansion of a malignant cell. This discussion focuses on the recently recognized role of a small but expanding family of PR-domain genes in tumorigenesis. The protein products of these genes are involved in...

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PMID: 10668202
DOI: 10.14670/hh-15.109

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