Article
Proinflammatory activation of neutrophils and monocytes by Helicobacter pylori is not associated with cagA, vacA or picB genotypes.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica - 1 Dec 1999
Hansen P S, Go M F, Varming K, Andersen L P, Graham D Y, Nielsen H
Abstract excerpt
Chronic Helicobacter pylori infection is associated with mucosal inflammation. The aim of the present study was to assess human neutrophil and monocyte activation induced by H. pylori strains with different virulence genotypes. Bacterial sonicates from 12 strains were used to induce phagocyte up-regulation of adherence molecule CD11b, assessed by fluorescence flow cytometry, and oxidative burst responses,...
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