Article
The cytokine response in THP-1 (monocyte) and HL-60 (neutrophil-differentiated) cells infected with different genotypes of Helicobacter pylori strains.
The Turkish journal of gastroenterology : the official journal of Turkish Society of Gastroenterology - 1 Jul 2015
Çalışkan Reyhan, Sayı Yazgan Ayça, Tokman Hrisi Bahar, Sofyalı Emre, Erzin Yusuf Ziya, Akgül Özer, Kurt Aykut, Kalaycı Fatma, Ziver Tevhide, Yüksel Pelin, Bal Kadir, Kocazeybek Bekir
Abstract excerpt
BACKGROUND/AIMS: Helicobacter pylori (H. pylori) is a microaerophilic bacterium related with peptic ulcer and gastric cancer. Its virulence factors include cytotoxin-associated gene A (CagA) and vacuolating cytotoxin gene A (VacA) proteins. Cytokine release inducted by H. pylori colonization has an important role in pathogenesis of H. pylori. The severity of gastric pathologies depends on the H. pylori genotypes...
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