Article
Methylenetetrahydrofolate reductase 677 C --> T polymorphism, plasma folate, vitamin B(12) concentrations, and risk of preeclampsia among black African women from Zimbabwe.
Molecular genetics and metabolism - 1 Jan 2000
Rajkovic A, Mahomed K, Rozen R, Malinow M R, King I B, Williams M A
Abstract excerpt
We conducted a case control study at Harare Maternity Hospital, Zimbabwe. We genotyped a total of 171 cases with preeclampsia or eclampsia and 185 normotensive control subjects for the methylenetetrahydrofolate reductase (MTHFR) 677 C --> T genotype. The wild-type allele frequency among cases and controls was 91.2 and 91.3%, respectively. Only one subject (0.3%) was homozygous for the 677 C --> T MTHFR genotype...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.