Article
Effect of catalase on hydrogen peroxide penetration into Pseudomonas aeruginosa biofilms.
Applied and environmental microbiology - 1 Feb 2000
Stewart P S, Roe F, Rayner J, Elkins J G, Lewandowski Z, Ochsner U A, Hassett D J
Abstract excerpt
The penetration of hydrogen peroxide into biofilms formed by wild-type and catalase-deficient Pseudomonas aeruginosa strains was measured using microelectrodes. A flowing stream of hydrogen peroxide (50 mM, 1 h) was unable to penetrate or kill wild-type biofilms but did penetrate and partially kill biofilms formed by an isogenic strain in which the katA gene was knocked out. Catalase protects aggregated bacteria...
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