Article
Quorum sensing in Pseudomonas aeruginosa controls expression of catalase and superoxide dismutase genes and mediates biofilm susceptibility to hydrogen peroxide.
Molecular microbiology - 1 Dec 1999
Hassett D J, Ma J F, Elkins J G, McDermott T R, Ochsner U A, West S E, Huang C T, Fredericks J, Burnett S, Stewart P S, McFeters G, Passador L, Iglewski B H
Abstract excerpt
Quorum sensing (QS) governs the production of virulence factors and the architecture and sodium dodecyl sulphate (SDS) resistance of biofilm-grown Pseudomonas aeruginosa. P. aeruginosa QS requires two transcriptional activator proteins known as LasR and RhlR and their cognate autoinducers PAI-1 (N-(3-oxododecanoyl)-L-homoserine lactone) and PAI-2 (N-butyryl-L-homoserine lactone) respectively. This study provides...
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