Article
The dprA gene is required for natural transformation of Helicobacter pylori.
FEMS immunology and medical microbiology - 1 Feb 2000
Smeets L C, Bijlsma J J, Kuipers E J, Vandenbroucke-Grauls C M, Kusters J G
Abstract excerpt
Genetic recombination in Helicobacter pylori is believed to be involved in host adaptation of this gastric pathogen and uptake of DNA by natural transformation can result in changes in virulence factors as well as antigenic variation. To elucidate the mechanisms involved in natural transformation we tested two genes with homology to known competence genes (dprA and traG) for their role in this process. Insertion...
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