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Article

Synergistic induction of mouse serum amyloid A3 promoter by the inflammatory mediators IL-1 and IL-6.

Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research - 1 Dec 1999

Huang J H, Liao W S

Abstract excerpt

Serum amyloid A (SAA), one of the major acute-phase proteins, increases several hundredfold in concentration in plasma following acute inflammation, primarily as a result of a 200-fold increase in its transcription rate. We have previously demonstrated that a 350-bp promoter fragment from the mouse SAA3 gene could confer conditioned medium-induced expression in cultured cells. The induction is mediated through a...

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PMID: 10638709
DOI: 10.1089/107999099312867

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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