Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

SAF-3, a novel splice variant of the SAF-1/MAZ/Pur-1 family, is expressed during inflammation.

The FEBS journal - 1 Aug 2009

Ray Alpana, Dhar Srijita, Shakya Arvind, Ray Papiya, Okada Yasunori, Ray Bimal K

Abstract excerpt

The Cys2His2-type zinc finger transcription factor serum amyloid A activating factor 1 [SAF-1, also known as MAZ (myc-associated zinc finger protein) or Pur-1 (purine binding factor-1)] plays an important role in regulation of a variety of inflammation-responsive genes. An SAF-2 splice variant acting as a negative regulator of SAF-1 was identified previously, and the present study reports the identification of a...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alternative Splicing
Share to Chondrocytes
Share to Cloning, Molecular

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Complementary

Share to Gene Library

Share to Inflammation

Share to Open Reading Frames

Share to Proto-Oncogene Proteins c-myc

Source

Identifiers

PMID: 19583771
DOI: 10.1111/j.1742-4658.2009.07136.x

Genes

MAZ

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

SAF-3, a novel splice variant of the SAF-1/MAZ/Pur-1 family, is expressed during inflammation.PMID 19583771Read ↗

Cytokine-responsive induction of SAF-1 activity is mediated by a mitogen-activated protein kinase signaling pathway.Semantic proximity Read ↗

Inflammation-responsive transcription factor SAF-1 activity is linked to the development of amyloid A amyloidosis.Semantic proximity Read ↗

Serum amyloid A, the major vertebrate acute‐phase reactantSemantic proximity Read ↗

Transcriptional induction of matrix metalloproteinase-9 in the chondrocyte and synoviocyte cells is regulated via a novel mechanism: evidence for functional cooperation between serum amyloid A-activating factor-1 and AP-1.Semantic proximity Read ↗

Essential role of STAT3 in cytokine‐driven NF‐κB‐mediated serum amyloid A gene expressionSemantic proximity Read ↗

SA-1, a nuclear protein encoded by one member of a novel gene family: molecular cloning and detection in hemopoietic organsSemantic proximity Read ↗

Activator protein 1 (Fos/Jun) functions in inflammatory bone and skin diseaseSemantic proximity Read ↗

Alternative transcripts of the SERPINA1 gene in alpha-1 antitrypsin deficiency.Semantic proximity Read ↗

Active transcription of the human FAS/CD95/TNFRSF6 gene involves the p53 familySemantic proximity Read ↗

A unique ISRE, in the TATA-less human Isg20 promoter, confers IRF-1-mediated responsiveness to both interferon type I and type IISemantic proximity Read ↗

Serum amyloid A-activating factor-1 (SAF-1) transgenic mice are prone to develop a severe form of inflammation-induced arthritis.Semantic proximity Read ↗

Synergistic induction of mouse serum amyloid A3 promoter by the inflammatory mediators IL-1 and IL-6.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.