Article
Normocortisolemic Cushing's syndrome initially presenting with increased glucocorticoid receptor numbers.
The Journal of clinical endocrinology and metabolism - 1 Jan 2000
Newfield R S, Kalaitzoglou G, Licholai T, Chilton D, Ashraf J, Thompson E B, New M I
Abstract excerpt
A girl who developed Cushingoid features in peripuberty, but was eucortisolemic, was previously reported to have markedly elevated lymphocyte glucocorticoid receptor sites per cell with normal binding affinity as a potential cause of her phenotype. Her circadian rhythm of cortisol and pituitary-adrenal axis were initially intact, but later proved to be dysregulated. The patient presented at age 10.8 yr with...
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