Article
Genes, cells and cytokines in resistance against development of toxoplasmic encephalitis.
Immunobiology - 1 Dec 1999
Suzuki Y
Abstract excerpt
Toxplasma gondii is an intracellular protozoan parasite which invades various organs including the central nervous system. Immunity is crucial for preventing development of toxoplasmic encephalitis (TE) following infection. IFN-gamma-mediated immune response plays a central role in the resistance. The activation of microglia and astrocytes by IFN-gamma or a combination of this cytokine with TNF-alpha appears to...
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