Article
Phenotypic correction of Fanconi anemia group C knockout mice.
Blood - 15 Jan 2000
Gush K A, Fu K L, Grompe M, Walsh C E
Abstract excerpt
Fanconi anemia (FA) is a genetic disorder characterized by bone marrow failure, congenital anomalies, and a predisposition to malignancy. FA cells demonstrate hypersensitivity to DNA cross-linking agents, such as mitomycin C (MMC). Mice with a targeted disruption of the FANCC gene (fancc -/- null...
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