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Article

Potential Role for Luman, the Cellular Homologue of Herpes Simplex Virus VP16 (α Gene <i>trans</i> -Inducing Factor), in Herpesvirus Latency

15 Jan 2000

Abstract excerpt

The cascade of herpes simplex virus (HSV) gene expression that results in viral replication begins with the activation of viral immediate-early (IE) genes by the virion-associated protein VP16. VP16 on its own is inefficient at associating with complexes formed on IE gene promoters and depends upon the cellular factor HCF for its activity. In this respect VP16 mimics the host basic leucine zipper (bZIP) protein...

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Identifiers

PMID: 10623756
DOI: 10.1128/jvi.74.2.934-943.2000

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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Potential Role for Luman, the Cellular Homologue of Herpes Simplex Virus VP16 (α Gene <i>trans</i> -Inducing Factor), in Herpesvirus LatencyPMID 10623756Read ↗

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