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Article

Tau in cerebrospinal fluid: a potential diagnostic marker in Alzheimer's disease.

Annals of neurology - 1 Oct 1995

Arai H, Terajima M, Miura M, Higuchi S, Muramatsu T, Machida N, Seiki H, Takase S, Clark C M, Lee V M

Abstract excerpt

Cerebrospinal fluid from 70 patients with Alzheimer's disease (AD) and 96 patients with non-AD neurological diseases as well as 19 normal control subjects was surveyed by sandwich enzyme-linked immunosorbent assay to quantitate levels of the microtubule-associated protein tau in cerebrospinal fluid. The tau level was significantly increased in AD patients as compared with that in patients with non-AD neurological...

Topics

Adult
Age of Onset
Aged
Aged, 80 and over
Alzheimer Disease
Apolipoproteins E
Biomarkers
Genotype
Humans
Immunoblotting
Middle Aged
tau Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 7574462
DOI: 10.1002/ana.410380414

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7574462-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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