Article
Antibodies to type II collagen and HLA disease susceptibility markers in rheumatoid arthritis.
Arthritis and rheumatism - 1 Dec 1999
Cook A D, Stockman A, Brand C A, Tait B D, Mackay I R, Muirden K D, Bernard C C, Rowley M J
Abstract excerpt
OBJECTIVE: To seek associations between antibodies to native and denatured type II collagen (NCII and DCII) and HLA in rheumatoid arthritis (RA). METHODS: One hundred fourteen patients with clinically well-defined RA were HLA-DR and DQ typed. Those who were DR4 positive were subtyped for DRB1*0401-*0408 alleles by polymerase chain reaction using allele-specific oligonucleotide probes. Antibodies to human NCII and...
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