An abnormal distribution of delta F508 genotypes in cystic fibrosis patient registries.

Article

An abnormal distribution of delta F508 genotypes in cystic fibrosis patient registries.

Annales de genetique - 1 Jan 1998

Feingold J, Guilloud-Bataille M, De Crozes D

Abstract excerpt

Delta F508 mutation of the CFTR gene is the most frequent deleterious allele involved in cystic fibrosis (CF). We have studied the distribution of the three genotypes, delta F508/delta F508, delta F508/x, x/x, in the American, Canadian and French data registries concerning CF; "x" represents the...

Topics

Adolescent
Adult
Alleles
Canada
Child
Child, Preschool
Cystic Fibrosis
Cystic Fibrosis Transmembrane Conductance Regulator
Female
France
Gene Frequency
Genotype
Humans
Infant
Infant, Newborn
Male
Mutation
Registries

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