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Article

Quasispecies development of Helicobacter pylori observed in paired isolates obtained years apart from the same host.

The Journal of infectious diseases - 1 Jan 2000

Kuipers E J, Israel D A, Kusters J G, Gerrits M M, Weel J, van Der Ende A, van Der Hulst R W, Wirth H P, Höök-Nikanne J, Thompson S A, Blaser M J

Abstract excerpt

Helicobacter pylori isolates show greater genetic diversity than other bacterial species studied, but the basis for this phenomenon is unknown. Whether detectable genomic mutation appears within an H. pylori population during persistent colonization was investigated. Paired H. pylori populations obtained across 7- to 10-year intervals from 13 patients were characterized by use of methods including polymerase...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 10608776
DOI: 10.1086/315173
PMCID: PMC2766531

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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