Article
Genotype Diversity and Quasispecies Development of Helicobacter pylori in a Single Host.
Japanese journal of infectious diseases - 1 Jan 2015
Farzi Nastaran, Malekian Tannaz, Alebouyeh Masoud, Vaziri Farzam, Zali Mohammad Reza
Abstract excerpt
Infection with different strains of Helocobacter pylori and emergence of new genomic variants during their long-term gastric colonization are assumed to be the main reasons for eradication failure. We used genotyping and arbitrarily primed PCR fingerprinting (RAPD) to detect relatedness and genetic variations among H. pylori single isolates from each patient in Iran. Multiplex-PCR amplification of gene alleles...
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