Article
p53 Expression and Relation to Human Papillomavirus Infection in Pingueculae, Pterygia, and Limbal Tumors
1 Dec 1999
Abstract excerpt
BACKGROUND: The tumor suppressor gene p53 is expressed without apoptosis in the limbal basal stem cells of all pterygia and limbal tumors and most pingueculae from which these growths seem to originate. Oncogenic human papillomaviruses (HPVs) have been found in pterygia and limbal tumors, and HPV and p53 overexpression commonly coexist in oropharyngeal and penile carcinomas. OBJECTIVE: To search for HPV DNA as a...
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