Article
Expression of p53 protein in pterygium.
European journal of ophthalmology - 1 Jan 2000
Onur C, Orhan D, Orhan M, Dizbay Sak S, Tulunay O, Irkeç M
Abstract excerpt
PURPOSE: The pathogenesis of pterygium is still not completely understood and many environmental factors, including ultraviolet (UV) radiation, play an important role in its etiology. Chronic exposure to UV radiation causes mutations in the p53 tumor suppressor gene, eventually leading to tumor formation. We analyzed the immunohistochemical expression of p53 proteins in pterygial tissues to determine the role of...
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