Article
Immunohistochemical study of p53, p21 and PCNA in pterygium.
Acta histochemica - 1 Apr 2001
Ueda Y, Kanazawa S, Kitaoka T, Dake Y, Ohira A, Ouertani A M, Amemiya T
Abstract excerpt
Since mutated p53 is one of the most frequent gene abnormalities in human cancer, we hypothesized that mutation of p53 may play an important role in growth and recurrence of pterygia, a dysplasia of the conjunctiva. Therefore, we compared pterygia of Japanese and Tunisian patients using antibodies against p53, p21 and proliferating cell nuclear antigen (PCNA). In Nagasaki, 21 pterygia of Japanese individuals were...
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