Article
Linkage of chromosome 1 markers to alcoholism-related phenotypes by sib pair linkage analysis of principal components.
Genetic epidemiology - 1 Jan 1999
Olson J M, Rao S, Jacobs K, Elston R C
Abstract excerpt
Using the Collaborative Study on the Genetics of Alcoholism data and affected-sib-pair linkage methods, Reich et al. [1998] reported linkage of alcohol dependence to a region near D1S1588 on chromosome 1. In this paper, we assessed the ability of multivariate sib-pair linkage analysis of the neurophysiologic measurements (including age and sex) to evaluate evidence for linkage to chromosome 1. Principal...
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