Article
Joint multipoint linkage analysis of multivariate qualitative and quantitative traits. II. Alcoholism and event-related potentials.
American journal of human genetics - 1 Oct 1999
Williams J T, Begleiter H, Porjesz B, Edenberg H J, Foroud T, Reich T, Goate A, Van Eerdewegh P, Almasy L, Blangero J
Abstract excerpt
The availability of robust quantitative biological markers that are correlated with qualitative psychiatric phenotypes can potentially improve the power of linkage methods to detect quantitative-trait loci influencing psychiatric disorders. We apply a variance-component method for joint multipoint linkage analysis of multivariate discrete and continuous traits to the extended pedigree data from the Collaborative...
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