Article
Comparison of GENEHUNTER and MFLINK for analysis of COGA linkage data.
Genetic epidemiology - 1 Jan 1999
Curtis D, Zhao J H, Sham P C
Abstract excerpt
We compared the NPLALL statistic from GENEHUNTER with two-point and three-point MALODs and MFLODs from MFLINK for all autosomal markers in the Collaborative Study on the Genetics of Alcoholism (COGA) data set. In general MFLINK produced more significant results than GENEHUNTER and implicated two regions containing candidate genes (ADH3 and DRD2). Many regions of interest identified in other studies reported at...
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