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Enhanced coexpression of YB‐1 and DNA topoisomerase II α genes in human colorectal carcinomas

19 Nov 1999

Abstract excerpt

The transcription factor YB-1 is expressed in a wide range of cell types and has been implicated in the regulation of various genes involved in cell proliferation. Nuclear expression of YB-1 is correlated with MDR-1 gene expression in breast cancer and osteosarcoma. In this study, we asked whether YB-1 expression is enhanced in human colorectral carcinoma and if it is associated with the expression of target...

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Identifiers

PMID: 10597187
DOI: 10.1002/(sici)1097-0215(19991210)83:6<732::aid-ijc6>3.0.co;2-#

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