Article
Transgenic plants expressing cationic peptide chimeras exhibit broad-spectrum resistance to phytopathogens.
Nature biotechnology - 1 Nov 2000
Osusky M, Zhou G, Osuska L, Hancock R E, Kay W W, Misra S
Abstract excerpt
Here we describe a strategy for engineering transgenic plants with broad-spectrum resistance to bacterial and fungal phytopathogens. We expressed a synthetic gene encoding a N terminus-modified, cecropin-melittin cationic peptide chimera (MsrA1), with broad-spectrum antimicrobial activity. The synthetic gene was introduced into two potato (Solanum tuberosum L.) cultivars, Desiree and Russet Burbank, stable...
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