Article
Activities of tobramycin and six other antibiotics against Pseudomonas aeruginosa isolates from patients with cystic fibrosis.
Antimicrobial agents and chemotherapy - 1 Dec 1999
Shawar R M, MacLeod D L, Garber R L, Burns J L, Stapp J R, Clausen C R, Tanaka S K
Abstract excerpt
The in vitro activity of tobramycin was compared with those of six other antimicrobial agents against 1,240 Pseudomonas aeruginosa isolates collected from 508 patients with cystic fibrosis during pretreatment visits as part of the phase III clinical trials of tobramycin solution for inhalation. The tobramycin MIC at which 50% of isolates are inhibited (MIC(50)) and MIC(90) were 1 and 8 microg/ml, respectively....
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