Article
Large-scale analysis of differential gene expression in the hindlimb muscles and diaphragm of mdx mouse.
Biochimica et biophysica acta - 3 Jan 2000
Tkatchenko A V, Le Cam G, Léger J J, Dechesne C A
Abstract excerpt
The mdx mouse is an animal model for Duchenne muscular dystrophy (DMD), which is caused by the absence of dystrophin. Mdx limb muscles substantially compensate for the lack of dystrophin while the diaphragm is affected like DMD skeletal muscles. To understand better the complex cascade of molecular events leading to muscle degeneration and compensatory processes in mdx muscles, we analyzed alterations of gene...
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